Methicillin – 5 μg Antibiotic Disc – Bioanalyse

Methicillin – 5 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 5 micrograms of methicillin, a penicillin antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to methicillin.

Methicillin is a narrow-spectrum antibiotic, meaning that it is only effective against a limited range of bacteria. It is primarily used to test for methicillin-resistant Staphylococcus aureus (MRSA), a Gram-positive bacterium that is resistant to many other antibiotics.

Interpretation of results:

| Zone of inhibition | Interpretation | |—|—|—| | ≥ 28 mm | Susceptible | | 23-27 mm | Intermediate | | < 23 mm | Resistant |

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Methicillin – 5 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis of MRSA infections. However, it is important to be aware of the potential limitations of the disc diffusion method. For example, some strains of MRSA may produce a small zone of inhibition around a methicillin disc, even though they are resistant to the antibiotic. Additionally, the results of the disc diffusion test can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

Additional information about methicillin:

Methicillin is a safe and effective antibiotic for most people. However, it is important to be aware of the potential side effects of methicillin before using it. Methicillin can cause side effects such as nausea, vomiting, diarrhea, and rash. In rare cases, methicillin can cause serious side effects such as anaphylaxis.

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