Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 5 micrograms of norfloxacin, a fluoroquinolone antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to norfloxacin.

Norfloxacin is a broad-spectrum antibiotic, meaning that it is effective against a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. It is used to treat a variety of infections, including:

• Urinary tract infections
• Gastrointestinal infections
• Respiratory infections
• Skin and soft tissue infections
• Sexually transmitted infections

Norfloxacin is also used to prevent infections before surgery.

Interpretation of results:

| Zone of inhibition | Interpretation | |—|—|—| | ≥ 21 mm | Susceptible | | 16-20 mm | Intermediate | | < 16 mm | Resistant |

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of a wide range of bacterial infections. However, it is important to be aware of the potential side effects of norfloxacin before using it. Norfloxacin can cause side effects such as:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Rash

In rare cases, norfloxacin can cause serious side effects such as:

• Seizures
• Tendon rupture
• Kidney damage

Limitations of the Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse:

• The disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.
• The disc diffusion method is not able to detect all bacteria that are resistant to norfloxacin. For example, some strains of Pseudomonas aeruginosa are resistant to norfloxacin, but they may not produce a zone of inhibition around a norfloxacin disc.
• The disc diffusion method can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

Additional information about norfloxacin:

Norfloxacin is a safe and effective antibiotic for most people when used as directed. However, it is important to be aware of the potential side effects of norfloxacin before using it. Norfloxacin is not recommended for people who are allergic to norfloxacin or other fluoroquinolone antibiotics. Norfloxacin is also not recommended for children under the age of 18, pregnant women, or breastfeeding women.

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