HEV-IGM Hormone Test Kit – ENZO

The ENZO HEV-IGM Hormone Test Kit is a qualitative enzyme-linked immunosorbent assay (ELISA) for the detection of hepatitis E virus (HEV) IgM antibodies in human serum or plasma. The kit is intended for in vitro diagnostic use.

HEV IgM antibodies are produced by the body in response to infection with HEV. They are typically detectable within 1-2 weeks of exposure to HEV and can persist for up to 6 months. A positive HEV IgM test result indicates that the person is in the acute phase of HEV infection.

The ENZO HEV-IGM Hormone Test Kit is a sensitive and specific assay for the detection of HEV IgM antibodies. It is based on the principle of sandwich ELISA. The kit contains two microplates coated with anti-HEV IgM antibodies. The first microplate is used to capture HEV IgM antibodies from the sample. The second microplate is used to detect the captured HEV IgM antibodies with a biotinylated anti-HEV IgM antibody and a streptavidin-horseradish peroxidase conjugate. The reaction is visualized with a tetramethylbenzidine (TMB) substrate. The presence of HEV IgM antibodies is indicated by the development of a blue color.

The ENZO HEV-IGM Hormone Test Kit is a valuable tool for the diagnosis of acute HEV infection. It can be used to identify people who are in the early stages of HEV infection and who are at risk of transmitting the virus to others.

The kit contains all of the reagents necessary to perform the test, including microplates, antibodies, conjugates, and substrates. The test procedure is simple and can be completed in approximately 2 hours. The kit is also relatively inexpensive, making it accessible to a wide range of laboratories.

Clinical significance of HEV-IGM positive:

A positive HEV IgM test result indicates that the person is in the acute phase of HEV infection. This means that the person is contagious to others.

When to order an HEV-IGM test:

An HEV-IGM test is typically ordered for people who have symptoms of acute HEV infection, such as jaundice, fatigue, and abdominal pain. It is also ordered for people who have been exposed to HEV, such as through travel to an area with high HEV prevalence or contact with an infected person.

How to interpret an HEV-IGM test result:

A positive HEV IgM test result indicates that the person is in the acute phase of HEV infection.

A negative HEV IgM test result indicates that the person is not in the acute phase of HEV infection or that the person has been infected with HEV but has not yet developed an immune response to the virus.

If a person has a negative HEV IgM test result, they should be tested for the presence of HEV total antibodies, which can indicate past infection or immunity.

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